Nothing comes between me and my Calvin’s — except a cool $6.5 million.

Designer Calvin Klein has decided to sell his minimalist-designed Chelsea office condo, which includes a large balcony and three sides of floor-to-ceiling windows that provide sweeping views from the World Trade Center across the Hudson River and up to Hudson Yards.

Located on the 18th floor of the 20-story Chelsea Arts Tower, the 3,898-square-foot office with a 382-square-foot covered terrace has been Klein’s executive office since the building was developed in 2006 by Jack Guttman and Young Woo. Architect Richard Gluckman designed the space, which has polished concrete floors.

Now, Stuart Siegel, the CBRE broker who was instrumental in its development at 545 W. 25th St. between Tenth and Eleventh avenues, is marketing the full-floor office along with colleague Matt Bergey. The asking price does not include the nearly $90,000 per year in common charges and taxes.

“In my 29 years in commercial real estate, I haven’t seen a space this meticulously crafted with unmatched panoramic views,” said Siegel.

On Monday, the doorman called up to the office before allowing us entry to the elevators. There are two plus a freight elevator used by the lower floor galleries that include the Marlborough.

A crane was used, however, to hoist up Klein’s metal conference table that spans some 24 feet. It will likely remain, Siegel said, as will the extensive custom metal walls and cabinetry that line one side of the space.

The entry area includes more metal cabinets on one side while a long metal desk against the window was being used by staffers enjoying the downtown view as they worked away on their laptops.

Out of the clouds and back on West 25th Street, where galleries, renovated offices and new apartment buildings line the sidewalks and the High Line overlooks the street, Law & Order SVU had taken over the parking, and I spotted rapper-actor Snoop Dogg with an entourage. “He’d love this loft,” Siegel said, as Snoop was whisked away. He would indeed.