The retail scene in downtown Manhattan is heating up — again.

TJX, the parent company of Marshalls and T.J. Maxx, has signed a lease to take over a huge swath of 140 West St.’s retail space, The Post has learned.

In what turned into the largest downtown retail deal of 2016, building owners Ben Shaoul, CEO of Magnum Real Estate, and partner CIM Group, signed a lease for 68,400 square feet to bring the store to life.

SL Green Realty Corp. and Jeff Sutton’s Nike deal at 650 Fifth Ave. squeaked by as the largest retail deal in all of Gotham City at 69,214 square feet – just 814 feet larger but meaningful in a real estate world where every square foot can be worth thousands of dollars.

The TJX store will occupy a small portion of the first floor — plus two lower levels.

The historic Verizon property sits on a full block bounded by Barclay, Vesey, West and Washington streets, and is surrounded by One and Seven World Trade Centers.

Goldman Sachs’ headquarters is located just across West Street.

The entrance will be at the corner of Vesey and Washington.

Peter Ripka and Richard Skulnik of Ripco Real Estate represented the TJX Corporation, while David Tricarico of Cushman & Wakefield represented the building owner.

Verizon owns the lower 10 floors.

TJX is expected to use the downtown space for its Marshalls nameplate, which had 1,027 stores as of Oct. 29.

The additional of Marshalls will make even hotter a retail scene already simmering with an influx of residential buildings and a cornucopia of assorted retail.

It joins Century 21, Zara, Urban Outfitters and Brooks Brothers — in addition to newcomer Saks Fifth Avenue — in a battle for the hundreds of thousands of downtown workers and residents.

As The Post previously reported, the expansive retail offering of 100,000 square feet in the building had been targeted by both Nike and Under Armour.

There is still space available, but the fate of those deals could not be immediately learned.

Asking rent for the ground floor was $350 a square foot — with the lower level at $100.

TJX shares have performed well over the past year, rising 13 percent to Friday’ s close at $75.93.

Same store sales in the third quarter ended Oct. 29 rose 5 percent. Overall sales rose 6.6 percent, to $5.3 billion.

The companies involved declined comment.