Investors who bought a stake in the 1.04 million square-foot 299 Park Ave. about 18 months ago are hoping to sell for a profit now that building values are bouncing upwards.

Boston-based Rockpoint Group has hired CB Richard Ellis to market its 49.5 percent interest in the UBS headquarters, which it purchased from UBS in January 2010.

That deal valued the building at just over $600 million, or $625 a foot. At the time, sources told The Post that Rockpoint paid out about $20 million in cash and assumed its share of a $325 million mortgage.

According to reports, that stake could now be worth as much as $550 million based on a value of $1,000 a foot.

CBRE brokers and a Rockpoint executive did not return calls for comment.

The property was developed by the Fisher Bros. family, which holds the majority share and runs the Class A building in cooperation with Rockpoint.