The D.E. Shaw Group has renewed its lease at 1166 Sixth Ave. for 195,375 square feet.

The privately owned global investment and technology firm has the entire fifth through the ninth floors in the 1.6-million-square-foot office building that sits between West 45 and West 46 streets.

The tenant was represented by Timothy Dempsey, Roger P. Griswold Jr. and Munish Viralam of CBRE.

The building, owned by Edward J. Minskoff Equities, was represented by Paul Glickman, Cynthia Wasserberger, Jonathan Fanuzzi and Diana Biasotti of JLL. The JLL team worked closely with Jeffrey Sussman of Minskoff.

Asking rents depend on floors and range from the high-$70s to mid-$80s per square foot.

Gensler architects is completing a redesign of the lobby, lighting, outdoor canopies and security at the tower while its upgraded telecom will be WiredScore Gold. The lobby will also house art including Roy Lichtenstein tapestries.

David Shaw and his wife, Beth Kobliner, a financial writer, are four years into the construction of a home, guesthouse, pool and tennis court in Hastings overlooking the Hudson River that has imported glass fences, geothermal heat and a secure underground garage and bunker.

The Saudi Arabian family-owned company that is buying the Sony Building at 550 Madison Ave. for more than $1.4 billion, the Olayan Group, is known for investments around the world and in NYC.

The family was partners with Starwood in the development and recent sale of the Baccarat Hotel. And, along with Mandarin Oriental, the Olayans purchased the Hotel Ritz in Madrid. Since 2007, the family has been an investor in Related Cos.

The son, Khaled Olayan, and three daughters — Hayat, Hutham and Lubna — of late founder Suliman S. Olayan lead the global conglomerate worth some $10 billion.

It is an active investor and partners with industrial, construction and consumer goods companies that range from Coca-Cola and Colgate Palmolive to Burger King and Cummins.

The sisters are also leading advocates for the health and education of women.

Toll Brothers City Living has signed a 5,000-square-foot lease for the entire 11th floor at 45 E. 20 St., where it will create a sales and marketing office for its upcoming condominium at 122 E. 23rd St.

Scott Sloves and Tyler Morss of CBRE represented Toll Brothers in conjunction with Josh Gelb in-house.

John D. Goodkind of Koeppel Rosen represented the building, a Rosen family investment that is also home to the nearby Eataly’s operator, the Batali & Bastianich Hospitality Group.

CoStar data show the asking rent at the building is $62 per square foot.

Sales for the 133-unit condominiums in the 18-story property will launch later this year. While the architect of record is SLCE, reports have Rem Koolhaas’s firm, Office for Metropolitan Architecture, led locally by Shohei Shigematsu, as the designer.

Financial market analysis firm Reorg Research has leased the entire 12th floor of 12,083 square feet at 11 E. 26th St. in NoMad.

The company is known for its financial research and is expanding from the nearby 1140 Broadway.

Michael Joseph and Taylor Bell of Colliers International represented the tenant in the 10-and-a-half-year deal that had an asking rent of $65 per square foot.

The building owner was represented by James Buslik of Adams & Co. “The building is right on Madison Square Park and practically sells itself,” said Buslik.

Local family office Ocean Road Advisors is targeting a move from the General Motors Building at 787 Fifth Ave. — right across East 59 Street to 650 Madison Ave.

The New York-based Meyer family investment vehicle is negotiating for 7,000 square feet on part of the 26th floor, sources said. The building asking rent is $165 per square foot.

Howard Hersch and Scott Panzer of JLL are representing the family funds and declined comment through a spokesman.

The spokesman also declined comment on behalf of the JLL team of Mitchell Konsker, Frank Doyle, David Kleiner and Dan Turkewitz that is representing the building owners.

The 27-story office building is owned by a venture that includes Vornado Realty Trust, Oxford Properties, Crown Acquisitions and Highgate Holdings.

Vornado’s Glen Weiss, Andrew Ackerman and Adam Frazier of Oxford oversee the JLL agency team.