Real estate tycoon Harry Macklowe’s proposed Midtown Manhattan skyscraper, dubbed Tower Fifth, is now likely to get skinnier — thanks to US sanctions against the Venezuelan regime.

After The Post reported Wednesday that Macklowe’s Tower Fifth skyscraper will be built partially in a space where the Venezuelan consulate now stands on East 51st Street, the Venezuelan Ambassador to the US tweeted out the story with some harsh words to the South American nation’s current leader Nicolas Maduro.

“None of [Venezuela’s] assets are for sale in the US,” Ambassador Carlos Vecchio tweeted with a link to The Post story.

“Maduro regime attempted to sell VZ consulate in NY, one of the usurper’s criminal acts that we stopped to protect assets of the nation,” said Vecchio, who was appointed by Maduro’s opposition leader Juan Guaidó, who the US recognizes as the interim president of the country.

He referred The Post’s report about the sale to Guaidó’s Assembly, he said.

The US State Department also chimed in Wednesday with an e-mail to The Post saying it is “unaware of any potential sale regarding a Venezuelan owned property.”

“The Foreign Missions Act requires all foreign missions to notify and obtain the approval of the Department’s Office of Foreign Missions before finalizing a sale of real property in the United States,” the State Department spokesman told The Post.

Macklowe, who is sailing on his yacht in Europe, did not immediately respond to an e-mail request for comment.

Earlier, he said it’s “done” when asked about any US government pushback to his plans to incorporate the Venezuelan consulate into the base of the proposed 1,556-foot-tall office tower.

He may now have to re-jigger his plan by buying the consulate’s air rights, or trade it for another property.

If approved, the proposed 1.3 million-square-foot tower will have an observatory, food hall, glass galleria spanning the block, an auditorium and offices.

Under the plan, a glass lobby will frame the side entrance of St. Patrick’s Cathedral, which is also selling some air rights.