More than 200 irate state Health Department workers are demanding that officials reconsider their group’s proposed move to a building near Ground Zero, which they say has a sickening history of “extreme contamination.”

In an angry petition sent yesterday to the state Office of General Services, which would oversee the move, 220 livid workers currently at 5 Penn Plaza blasted the department’s proposed move to 90 Church St.

The members said the building – which was hit by the landing gear of one of the two hijacked 9/11 airliners – suffered structural damages and had been plagued by asbestos contamination, lead dust, fungi, fiberglass dust, heavy metals, mercury and bacteria.

The workers say the move could endanger their physical and mental health and that they would be forced to work for the next decade beside the largest construction site in the city – the redevelopment of the World Trade Center area.

“Noise, air pollution and congestion from the site . . . and trucks that will be continuously unloading materials” are cause for “great apprehension,” they said in the petition.

“People with respiratory conditions, especially asthmatics, are very fearful of moving [and] the harmful psychological consequences of such a move should not be underestimated.”

The group – which represents about half of the department’s 400 managers, researchers and clerical workers at Penn Plaza currently slated for relocation – wants the department to look for a “different, healthier location” for its new offices.

“How ironic is it that health professionals are being asked to move to an unsafe structure and an unsafe location?” said Denyce Duncan Lacy, a spokeswoman for the Public Employees Federation, one of the unions representing the state workers.

A recent study showed that traffic and noise would be inevitable byproducts of the massive downtown redevelopment. When rebuilding efforts get under way, planners expect almost simultaneous construction of the Freedom Tower and four nearby skyscrapers, as well as the trade center memorial, a permanent PATH station and a transit center.

The 15-story, 1.1-million- square-foot limestone monolith at 90 Church St. previously housed the Postal Service and other federal offices.

It was considered damaged but stable immediately after the attacks of 9/11 and was completely renovated last year during a cleanup that included ripping out all its interior walls.

An official for Ambiant Laboratory, which tested the building afterward, told The Post its previous owners, Boston Properties, left it clean as a whistle.

“On a scale of one to 10, they were an 11,” said Ambiant Vice President John Leitner.

Boston Properties Vice President Robert Selsam said the building was restored “to its pre-9/11 condition.”

Calls to the state health commissioner’s office were not immediately returned.